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36NB

Crystal structure of the NKX2-1 homeodomain bound to a palindromic DNA recognition sequence

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Homeobox protein Nkx-2.1polymer607490.74UniProt (P43699)
Pfam (PF00046)
Homo sapiens (human)Homeobox protein NK-2 homolog A,Thyroid nuclear factor 1,Thyroid transcription factor 1,TTF-1,Thyroid-specific enhancer-binding protein,T/EBP
2E, G
(E, G)
DAN TCAAGTGGGCCCCACTTGApolymer195805.82Homo sapiens
3F, H
(F, H)
DNA TCAAGTGGGGCCCACTTGApolymer195845.82Homo sapiens
4I
(A)
waterwater18.01Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight53266.1
All*Total formula weight53266.1
*Water molecules are not included.

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PDB entries from 2026-09-09

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