36KM

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with spirocyclic inhibitor 15

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein deacetylase HDAC6	polymer	1081	118515.9	2	UniProt (F8W4B7)	Danio rerio (zebrafish)	Tubulin-lysine deacetylase HDAC6
2	C, G (A, B)	3,5-difluoro-N-hydroxy-4-[(8-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl]benzamide	non-polymer		430.4	2	Chemie (A1DJ1)
3	D, J (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
4	E, F, K, L (A, B)	POTASSIUM ION	non-polymer		39.1	4	Chemie (K) PubChem (813)
5	H, I (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	M, N (A, B)	water	water		18.0	329	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	237031.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1272.2
All*	Total formula weight	238304.1

*Water molecules are not included.