36KK
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with spirocyclic inhibitor 14
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein deacetylase HDAC6 | polymer | 1081 | 118515.9 | 2 | UniProt (F8W4B7) | Danio rerio (zebrafish) | Tubulin-lysine deacetylase HDAC6 |
| 2 | C, H (A, B) | 3-fluoro-N-hydroxy-4-({4-oxo-1-phenyl-8-[(pyridin-3-yl)methyl]-1,3,8-triazaspiro[4.5]decan-3-yl}methyl)benzamide | non-polymer | 489.5 | 2 | Chemie (A1DKB) | |||
| 3 | D, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 5 | F, G, K, L (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) PubChem (813) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 237031.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1390.4 | |
| All* | Total formula weight | 238422.3 |
