35YH
Crystal structure of covalent inhibitor 3-(2-chloroacetamido)-N-(3-hydroxyphenyl)benzamide bound to Ubiquitin C-terminal Hydrolase-L3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, A, C, D) | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | polymer | 238 | 26998.4 | 4 | UniProt (P15374) Pfam (PF01088) | Homo sapiens (human) | UCH-L3,Ubiquitin thioesterase L3 |
| 2 | E, F, G, H (B, A, C, D) | 3-(2-chloroacetamido)-N-(3-hydroxyphenyl)benzamide | non-polymer | 304.7 | 4 | Chemie (A1DIP) | |||
| 3 | I, J, K, L (B, A, C, D) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
B, A, C, D: 1 - 230 (UniProt: P15374)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 107993.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1218.9 | |
| All* | Total formula weight | 109212.7 |
