35WFEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Chk1 | polymer | 280 | 32381.3 | 1 | UniProt (O14757) Pfam (PF00069) | Homo sapiens (human) | CHK1 checkpoint homolog,Cell cycle checkpoint kinase,Checkpoint kinase-1 |
| 2 | B (A) | prexasertib | non-polymer | 365.4 | 1 | Chemie (A1DNH) | |||
| 3 | C, D, E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) PubChem (8117) | |||
| 4 | F, G, H, I, J... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) PubChem (753) | |||
| 5 | L, M, N, O, P... (A) | ETHANOL | non-polymer | 46.1 | 8 | Chemie (EOH) | |||
| 6 | T, U, V, W, X... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 7 | AA (A) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 1 - 274 (UniProt: O14757)
| PDB | External Database | Details |
|---|---|---|
| Glu 275 | - | expression tag |
| Asn 276 | - | expression tag |
| Leu 277 | - | expression tag |
| Tyr 278 | - | expression tag |
| Phe 279 | - | expression tag |
| Gln 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32381.3 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2039.3 | |
| All* | Total formula weight | 34420.6 |
