34CO
Homo sapiens Eukaryotic translation initiation factor 4E (eIF4E) in complex with synthetic mRNA cap analogs
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Eukaryotic translation initiation factor 4E | polymer | 193 | 22444.5 | 4 | UniProt (P06730) Pfam (PF01652) | Homo sapiens (human) | eIF-4E,eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein |
| 2 | E, F, G, H (A, B, C, D) | [(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-2-[[[[2-[2-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-9-yl)ethoxy]ethoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-4-methoxy-oxolan-3-yl] [5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 1102.7 | 4 | Chemie (A1KQY) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 28 - 217 (UniProt: P06730)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
| Met 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89778.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 4410.7 | |
| All* | Total formula weight | 94188.7 |
