34CL
Crystal structure of human Cathepsin L in complex with 3-(4-bromophenyl)-2-methylpropanamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cathepsin L | polymer | 220 | 24177.7 | 4 | UniProt (P07711) | Homo sapiens (human) | |
| 2 | E, N, X, Z (A, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | F, G, H, K, P... (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 8 | Chemie (PEG) PubChem (8117) | |||
| 4 | I, J, U, W, Y (B, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) PubChem (679) | |||
| 5 | L, M, T (B, C) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 6 | O (C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 7 | V (D) | (2R)-3-(4-bromophenyl)-2-methylpropanamide | non-polymer | 242.1 | 1 | Chemie (A1DOS) | |||
| 8 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 220 (UniProt: P07711)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Thr 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96710.7 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2374.8 | |
| All* | Total formula weight | 99085.5 |
