34CJ
Crystal structure of human Cathepsin L in complex with 2-(benzimidazol-1-yl)-N-methylacetamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cathepsin L | polymer | 220 | 24177.7 | 4 | UniProt (P07711) | Homo sapiens (human) | |
| 2 | E, G (A, B) | 2-(1H-benzimidazol-1-yl)-N-methylacetamide | non-polymer | 189.2 | 2 | Chemie (WRM) PubChem (40694280) | |||
| 3 | F, N, V (A, B, D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 4 | H, J, O, P (B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | I, K, L, S (B, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) PubChem (679) | |||
| 6 | M, Q, T (B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) PubChem (8117) | |||
| 7 | R, U (C, D) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) PubChem (62551) | |||
| 8 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 560 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 220 (UniProt: P07711)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Thr 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96710.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2184.7 | |
| All* | Total formula weight | 98895.4 |
