33SD
Immune complex comprising the HRSV preF trimer (SC-DM) and the monoclonal antibody Lor69 - Obtained by cryo-EM
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, B, C) | Fusion glycoprotein F0 | polymer | 522 | 57338.4 | 3 | UniProt (P03420) | Respiratory syncytial virus | |
| 2 | B, E, H (H, D, E) | Lor69 Heavy Chain | polymer | 121 | 13104.4 | 3 | Homo sapiens | ||
| 3 | C, F, I (L, F, G) | Lor69 Light Chain | polymer | 107 | 11822.2 | 3 | Homo sapiens | ||
| 4 | J, K, L, M, N... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, B, C: 1 - 522 (UniProt: P03420)
| PDB | External Database | Details |
|---|---|---|
| Lys 66 | Glu 66 | conflict |
| Ile 67 | Asn 67 | conflict |
| Ile 76 | Val 76 | conflict |
| Ala 102 | Pro 102 | conflict |
| Gln 106 | Arg 106 | conflict |
| - | Arg 109 | deletion |
| - | Glu 110 | deletion |
| - | Leu 111 | deletion |
| - | Pro 112 | deletion |
| - | Arg 113 | deletion |
| - | Phe 114 | deletion |
| - | Met 115 | deletion |
| - | Asn 116 | deletion |
| - | Tyr 117 | deletion |
| - | Thr 118 | deletion |
| - | Leu 119 | deletion |
| - | Asn 120 | deletion |
| - | Asn 121 | deletion |
| - | Ala 122 | deletion |
| - | Lys 123 | deletion |
| - | Lys 124 | deletion |
| - | Thr 125 | deletion |
| - | Asn 126 | deletion |
| - | Val 127 | deletion |
| - | Thr 128 | deletion |
| - | Leu 129 | deletion |
| - | Ser 130 | deletion |
| Gly 109 | Lys 131 | linker |
| Ser 110 | Lys 132 | linker |
| Gly 111 | Arg 133 | linker |
| Ser 112 | Lys 134 | linker |
| Gly 113 | Arg 135 | linker |
| Ser 115 | Phe 137 | conflict |
| Pro 193 | Ser 215 | conflict |
| Val 357 | Ile 379 | conflict |
| Val 425 | Met 447 | conflict |
| Ser 492 | - | insertion |
| Ala 493 | His 514 | conflict |
| Ile 494 | Asn 515 | conflict |
| Gly 495 | Val 516 | conflict |
| Gly 496 | Asn 517 | conflict |
| Tyr 497 | Ala 518 | conflict |
| Ile 498 | Gly 519 | conflict |
| Pro 499 | Lys 520 | conflict |
| Glu 500 | Ser 521 | conflict |
| Ala 501 | Thr 522 | conflict |
| Pro 502 | Thr 523 | conflict |
| Arg 503 | Asn 524 | conflict |
| Asp 504 | Ile 525 | conflict |
| Gly 505 | Met 526 | conflict |
| Gln 506 | Ile 527 | conflict |
| Ala 507 | Thr 528 | conflict |
| Tyr 508 | Thr 529 | conflict |
| Val 509 | Ile 530 | conflict |
| Arg 510 | Ile 531 | conflict |
| Lys 511 | Ile 532 | conflict |
| Asp 512 | Val 533 | conflict |
| Gly 513 | Ile 534 | conflict |
| Glu 514 | Ile 535 | conflict |
| Trp 515 | Val 536 | conflict |
| Val 516 | Ile 537 | conflict |
| Thr 520 | - | insertion |
| Phe 521 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 246795.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 248785.9 |
