32QB

Cryo-EM structure of Saccharomyces cerevisiae Erv14-Qdr2 complex in lipid nanodiscs (single Erv14 assembly)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ER-derived vesicles protein ERV14	polymer	146	16940.9	1	UniProt (P53173) Pfam (PF03311)	Saccharomyces cerevisiae (brewer's yeast)
2	B (B)	Quinidine resistance protein 2	polymer	549	60527.6	1	UniProt (P40474) Pfam (PF07690)	Saccharomyces cerevisiae (brewer's yeast)
3	C, D, E, H, I... (A, B)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	7	Chemie (Y01) PubChem (65082)
4	F, G (B)	ERGOSTEROL	non-polymer		396.6	2	Chemie (ERG) PubChem (444679)
5	K (B)	(2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate	non-polymer		382.4	1	Chemie (NKN) PubChem (9547180)

Sequence modifications

A: 1 - 138 (UniProt: P53173)

PDB	External Database	Details
Asp 139	-	expression tag
Tyr 140	-	expression tag
Lys 141	-	expression tag
Asp 142	-	expression tag
Asp 143	-	expression tag
Asp 144	-	expression tag
Asp 145	-	expression tag
Lys 146	-	expression tag

B: 1 - 542 (UniProt: P40474)

PDB	External Database	Details
Gly 543	-	expression tag
Glu 544	-	expression tag
Asn 545	-	expression tag
Leu 546	-	expression tag
Tyr 547	-	expression tag
Phe 548	-	expression tag
Gln 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77468.5
Non-Polymers*	Number of molecules	10
	Total formula weight	4582.8
All*	Total formula weight	82051.3

*Water molecules are not included.