32DY
RAD52 N-terminal domain in complex with compound FORX-12-864
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | DNA repair protein RAD52 homolog | polymer | 215 | 23597.6 | 22 | UniProt (P43351) Pfam (PF04098) | Homo sapiens (human) | |
| 2 | BA, CB, DC, FA, FB... (B, J, R, C, K...) | 2-[3-[2-[2-[3-[5-carboxy-4-[[2-fluoranyl-4-(prop-2-enoylamino)phenyl]methyl]-1,3-thiazol-2-yl]phenoxy]ethyl-methyl-amino]ethoxy]phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid | non-polymer | 716.8 | 22 | Chemie (A1KDB) | |||
| 3 | AB, AC, BC, CA, DA... (I, Q, B, J, R...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 29 | Chemie (EDO) | |||
| 4 | AA, BB, CC, EA, EB... (A, I, Q, B, J...) | CHLORIDE ION | non-polymer | 35.5 | 24 | Chemie (CL) PubChem (312) | |||
| 5 | AD, BD, CD, DD, ED... (H, I, J, K, L...) | water | water | 18.0 | 1272 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V: 1 - 212 (UniProt: P43351)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 102 | Lys 102 | engineered mutation |
| Ala 133 | Lys 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 22 |
| Total formula weight | 519146.8 | |
| Non-Polymers* | Number of molecules | 75 |
| Total formula weight | 18420.4 | |
| All* | Total formula weight | 537567.2 |
