32DW
RAD52 N-terminal domain in complex with compound FORX-12-027
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | DNA repair protein RAD52 homolog | polymer | 215 | 23597.6 | 22 | UniProt (P43351) | Homo sapiens (human) | |
| 2 | AC, BB, CB, CE, DB... (J, E, T, K, P...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 51 | Chemie (EDO) | |||
| 3 | AA, AB, BE, DD, EA... (A, E, T, P, B...) | 2-[3-[5-[3-(5-carboxy-4-methyl-1,3-thiazol-2-yl)phenoxy]pentoxy]phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid | non-polymer | 538.6 | 22 | Chemie (A1KDF) | |||
| 4 | AD, BA, BC, EE, FE... (O, A, J, T, E...) | MAGNESIUM ION | non-polymer | 24.3 | 20 | Chemie (MG) PubChem (888) | |||
| 5 | AE, BD, CA, CC, CD... (S, O, A, J, T...) | CHLORIDE ION | non-polymer | 35.5 | 36 | Chemie (CL) PubChem (312) | |||
| 6 | AF, BF, CF, DF, EF... (F, G, H, I, J...) | water | water | 18.0 | 1249 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V: 1 - 212 (UniProt: P43351)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 102 | Lys 102 | engineered mutation |
| Ala 133 | Lys 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 22 |
| Total formula weight | 519146.8 | |
| Non-Polymers* | Number of molecules | 129 |
| Total formula weight | 16777.8 | |
| All* | Total formula weight | 535924.6 |
