32DH
Crystal structure of YAP1(165-209) in complex with LATS2(511-522_C513S)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcriptional coactivator YAP1 | polymer | 49 | 5529.2 | 1 | UniProt (P46937) Pfam (PF00397) | Homo sapiens (human) | Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
| 2 | B (L) | Serine/threonine-protein kinase LATS2 | polymer | 13 | 1474.8 | 1 | UniProt (Q9NRM7) | Homo sapiens | Kinase phosphorylated during mitosis protein,Large tumor suppressor homolog 2,Serine/threonine-protein kinase kpm,Warts-like kinase |
| 3 | C, D (A, L) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 165 - 209 (UniProt: P46937)
L: 2 - 13 (UniProt: Q9NRM7)
| PDB | External Database | Details |
|---|---|---|
| Gly 161 | - | expression tag |
| Ala 162 | - | expression tag |
| Met 163 | - | expression tag |
| Gly 164 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| Ser 4 | Cys 513 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 7003.9 | |
| All* | Total formula weight | 7003.9 |
