32AW

Crystal structure of human CDK9/cyclin K in complex with NVP-2

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Cyclin-dependent kinase 9	polymer	374	43045.6	3	UniProt (A0A096P1Z7)	Homo sapiens (human)	Cell division protein kinase 9
2	B, D, F (B, D, F)	Cyclin-K	polymer	268	31429.2	3	UniProt (O75909)	Homo sapiens (human)
3	G, H, I (A, C, E)	4-[[[6-[5-chloranyl-2-[[4-[[(2~{R})-1-methoxypropan-2-yl]amino]phenyl]amino]pyridin-4-yl]pyridin-2-yl]amino]methyl]oxane-4-carbonitrile	non-polymer		507.0	3	Chemie (A1KBG)

Sequence modifications

A, C, E: 0 - 372 (UniProt: A0A096P1Z7)

PDB	External Database	Details
Gly -1	-	expression tag

B, D, F: 1 - 267 (UniProt: O75909)

PDB	External Database	Details
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	223424.3
Non-Polymers*	Number of molecules	3
	Total formula weight	1521.1
All*	Total formula weight	224945.4

*Water molecules are not included.