31RU
Crystal structure of PIM1 kinase in complex with compound 20
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 313 | 35590.5 | 1 | UniProt (P11309) | Homo sapiens (human) | |
| 2 | B (Q) | ALA-ARG-LYS-ARG-ARG-ARG-HIS-PRO-SER-GLY-PRO-PRO-THR-ALA | polymer | 14 | 1592.8 | 1 | Homo sapiens | ||
| 3 | C (A) | 6-chloranyl-3-[4-(1~{H}-indol-3-yl)-1~{H}-pyrazol-5-yl]quinazolin-4-one | non-polymer | 361.8 | 1 | Chemie (A1KBF) | |||
| 4 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | F, G (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | H, I (A, Q) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Gly 250 | Arg 250 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37183.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 678.0 | |
| All* | Total formula weight | 37861.4 |
