31EL

NSP14 IN COMPLEX WITH LIGAND MAVDA-K-197

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Guanine-N7 methyltransferase nsp14	polymer	529	59973.7	2	UniProt (P0DTD1)	SARS-CoV-2 pseudovirus	Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN
2	C, D, E, I, J... (A, B)	ZINC ION	non-polymer		65.4	7	Chemie (ZN) PubChem (32051)
3	F, M (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH) PubChem (439155)
4	G, N (A, B)	1-methyl-~{N}-[3-methyl-4-(6-methyl-[1,3]oxazolo[5,4-c]pyridin-2-yl)phenyl]-2-oxidanylidene-3~{H}-indole-5-sulfonamide	non-polymer		448.5	2	Chemie (A1J82)
5	H, O, P (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	Q, R (A, B)	water	water		18.0	55	Chemie (HOH)

Sequence modifications

A, B: 1 - 527 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -1	-	expression tag
Met 0	-	expression tag
Ala 90	Asp 6015	engineered mutation
Ala 92	Glu 6017	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119947.4
Non-Polymers*	Number of molecules	14
	Total formula weight	2309.9
All*	Total formula weight	122257.2

*Water molecules are not included.