30TA
Crystal structure of hCA II in complex with 1-Aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 262 | 29477.3 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 3 | C (A) | MERCURIBENZOIC ACID | non-polymer | 321.7 | 1 | Chemie (MBO) PubChem (8747) | |||
| 4 | D (A) | (1~{S})-6,7-dimethoxy-1-phenyl-3,4-dihydro-1~{H}-isoquinoline-2-sulfonamide | non-polymer | 348.4 | 1 | Chemie (A1J8Z) | |||
| 5 | E (A) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29477.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 735.5 | |
| All* | Total formula weight | 30212.8 |
