30DR

Dynein-Dynactin-RAB11FIP3 complex - composite

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (1, 2)	Rab11 family-interacting protein 3	polymer	793	86452.9	2	UniProt (O75154)	Homo sapiens (human)	FIP3,FIP3-Rab11,Rab11-FIP3,Arfophilin-1,EF hands-containing Rab-interacting protein,Eferin,MU-MB-17.148
2	C, D, E, F, G... (A, B, C, D, E...)	ARP1 actin related protein 1 homolog A	polymer	376	42670.7	8	UniProt (F2Z5G5)	Sus scrofa (pig)
3	J (H)	Actin, cytoplasmic 1	polymer	375	41782.7	1	UniProt (Q6QAQ1)	Sus scrofa (pig)	Beta-actin
4	L (J)	Arp11	polymer	417	46250.8	1	UniProt (I3LHK5)	Sus scrofa (pig)
5	M (K)	Capping protein (Actin filament) muscle Z-line, alpha 1	polymer	286	33059.8	1	UniProt (A0PFK5)	Sus scrofa (pig)	F-actin capping protein alpha 1 subunit,F-actin capping protein subunit alpha 1
6	N (L)	F-actin-capping protein subunit beta	polymer	272	30669.8	1	UniProt (A0PFK7)	Sus scrofa (pig)	CapZ beta
7	O, P, R, S, X (M, N, P, Q, V)	Dynactin subunit 2	polymer	405	44732.5	5	UniProt (A0A5G2QD80)	Sus scrofa (pig)
8	Q, T (O, R)	Dynactin subunit 3	polymer	186	21192.5	2	UniProt (F1SEC0)	Sus scrofa (pig)	Dynactin subunit 3 isoform 1
9	U, V (S, T)	Dynactin subunit 1	polymer	1281	142015.5	2	UniProt (A0A287B8J2)	Sus scrofa (pig)	150 kDa dynein-associated polypeptide,p150-glued
10	W (U)	Dynactin 6	polymer	190	20703.9	1	UniProt (D0G6S1)	Sus scrofa (pig)
11	Y (W)	Dynactin subunit 5	polymer	182	20150.5	1	UniProt (A0A286ZK88)	Sus scrofa (pig)
12	Z (Y)	Dynactin subunit 4	polymer	467	52920.4	1	UniProt (A0A4X1TB62)	Sus scrofa (pig)	Dynactin subunit 4
13	AA, BA, FA, GA (e, f, m, n)	Cytoplasmic dynein 1 heavy chain 1	polymer	4646	533055.1	4	UniProt (Q14204)	Homo sapiens (human)	Cytoplasmic dynein heavy chain 1,Dynein heavy chain,cytosolic
14	CA, DA, HA, IA (g, h, o, p)	Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2	polymer	612	68514.2	4	UniProt (Q13409)	Homo sapiens (human)	Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2,cytosolic,DH IC-2
15	EA, JA, KA (j, q, r)	Cytoplasmic dynein 1 light intermediate chain 2	polymer	492	54173.2	3	UniProt (O43237)	Homo sapiens (human)	Dynein light intermediate chain 2,cytosolic,LIC-2,LIC53/55
16	LA, MA, NA, OA (s, t, w, z)	Dynein light chain roadblock-type 1	polymer	96	10934.6	4	UniProt (Q9NP97)	Homo sapiens (human)	Bithoraxoid-like protein,BLP,Dynein light chain 2A,cytoplasmic,Dynein-associated protein Km23,Roadblock domain-containing protein 1

Sequence modifications

1, 2: 1 - 756 (UniProt: O75154)

PDB	External Database	Details
Met -36	-	initiating methionine
Trp -35	-	expression tag
Ser -34	-	expression tag
His -33	-	expression tag
Pro -32	-	expression tag
Gln -31	-	expression tag
Phe -30	-	expression tag
Glu -29	-	expression tag
Lys -28	-	expression tag
Gly -27	-	expression tag
Ser -26	-	expression tag
Ala -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Ala -22	-	expression tag
Ala -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
Gly -18	-	expression tag
Ala -17	-	expression tag
Gly -16	-	expression tag
Trp -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
Pro -12	-	expression tag
Gln -11	-	expression tag
Phe -10	-	expression tag
Glu -9	-	expression tag
Lys -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
Val -5	-	expression tag
Leu -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Pro 0	-	expression tag

M, N, P, Q, V: 1 - 405 (UniProt: A0A5G2QD80)

PDB	External Database	Details
Val 7	Ala 7	conflict

e, f, m, n: 1 - 4646 (UniProt: Q14204)

PDB	External Database	Details
Glu 1567	Arg 1567	engineered mutation
Glu 1610	Lys 1610	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	41
	Total formula weight	3922422.7
All*	Total formula weight	3922422.7

*Water molecules are not included.