30AZ

Structure of the occluded-state soluble domain of human Adenylyl cyclase 9 in complex with stimulatory G protein, ATPalphaS, and forskolin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adenylate cyclase type 9	polymer	1353	150881.3	1	UniProt (O60503)	Homo sapiens (human)	ATP pyrophosphate-lyase 9,Adenylate cyclase type IX,ACIX,Adenylyl cyclase 9,AC9
2	B (B)	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	polymer	404	46988.8	1	UniProt (P04896)	Bos taurus (domestic cattle)	Adenylate cyclase-stimulating G alpha protein
3	C (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
4	D (B)	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE	non-polymer		539.2	1	Chemie (GSP)

Sequence modifications

B: 1 - 394 (UniProt: P04896)

PDB	External Database	Details
Gly 395	-	expression tag
Gly 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	197870.1
Non-Polymers*	Number of molecules	2
	Total formula weight	563.6
All*	Total formula weight	198433.6

*Water molecules are not included.