30AE
Complex between IgE-Fc and anti-IgE Fab aeFab92
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | aeFab92 heavy chain | polymer | 215 | 22769.5 | 1 | Oryctolagus cuniculus | ||
| 2 | B (L) | aeFab92 light chain | polymer | 214 | 22690.1 | 1 | Oryctolagus cuniculus | ||
| 3 | C, D (B, A) | Isoform 1 of Immunoglobulin heavy constant epsilon | polymer | 327 | 36354.8 | 2 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (human) | Ig epsilon chain C region,Ig epsilon chain C region ND |
| 4 | E (C) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G34442SS) | |||
| 5 | F (D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 707.6 | 1 | In PDB GlyTouCan (G00027MO) |
Sequence modifications
B, A: 224 - 547 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Asp 222 | - | expression tag |
| Ile 223 | - | expression tag |
| Ala 225 | Cys 105 | engineered mutation |
| Gln 265 | Asn 146 | engineered mutation |
| Gln 371 | Asn 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118169.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1780.6 | |
| All* | Total formula weight | 119949.7 |
