30AC
Complex between IgE-Fc and anti-IgE Fab aeFab67
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 1 of Immunoglobulin heavy constant epsilon | polymer | 327 | 36354.8 | 2 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (human) | Ig epsilon chain C region,Ig epsilon chain C region ND |
| 2 | C, E (H, C) | aeFab67 heavy chain | polymer | 211 | 22231.8 | 2 | Oryctolagus cuniculus | ||
| 3 | D, F (L, D) | aeFab67 light chain | polymer | 214 | 22716.2 | 2 | Oryctolagus cuniculus | ||
| 4 | G, H (E, F) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 5 | I, J (L, D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) PubChem (8200) |
Sequence modifications
A, B: 224 - 547 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Asp 222 | - | expression tag |
| Ile 223 | - | expression tag |
| Ala 225 | Cys 105 | engineered mutation |
| Gln 265 | Asn 146 | engineered mutation |
| Gln 371 | Asn 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 162605.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1821.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 388.5 | |
| All* | Total formula weight | 164815.8 |
