2ZYB
Crystal structure of phenylimidazo pyrazin 2 bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase LCK | polymer | 285 | 33065.6 | 1 | UniProt (P06239) Pfam (PF07714) | Homo sapiens (Human) | Lymphocyte cell-specific protein-tyrosine kinase, p56-LCK, LSK, T cell-specific protein-tyrosine kinase |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine | non-polymer | 314.4 | 1 | Chemie (KSL) | |||
| 4 | D (A) | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33065.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 410.4 | |
| All* | Total formula weight | 33476.0 |
