2ZY0

Crystal structure of the human RXR alpha ligand binding domain bound to a synthetic agonist compound and a coactivator peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Retinoic acid receptor RXR-alpha	polymer	240	26856.0	2	UniProt (P19793) Pfam (PF00104) In PDB	Homo sapiens (human)	Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1
2	B, D	GRIP1 from Nuclear receptor coactivator 2	polymer	13	1579.9	2	UniProt (Q15596) In PDB		NCoA-2, Transcriptional intermediary factor 2, hTIF2
3	A, C	4-[2-(1,1,3,3-tetramethyl-2,3-dihydro-1H-1,3-benzodisilol-5-yl)-1,3-dioxolan-2-yl]benzoic acid	non-polymer		398.6	2	Chemie (21P)
4		water	water		18.0	26	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	56871.8
Non-Polymers*	Number of molecules	2
	Total formula weight	797.2
All*	Total formula weight	57669.0

*Water molecules are not included.