2ZXZ
Crystal structure of the human RXR alpha ligand binding domain bound to a synthetic agonist compound and a coactivator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 240 | 26856.0 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1 |
| 2 | B (B) | GRIP1 from Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | NCoA-2, Transcriptional intermediary factor 2, hTIF2 | |
| 3 | C (A) | 4-[2-(1,1,3,3-tetramethyl-2,3-dihydro-1H-inden-5-yl)-1,3-dioxolan-2-yl]benzoic acid | non-polymer | 366.4 | 1 | Chemie (P26) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28435.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 366.4 | |
| All* | Total formula weight | 28802.4 |
