2ZXF
Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with AP4A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycyl-tRNA synthetase | polymer | 693 | 78704.8 | 1 | UniProt (P41250) Pfam (PF00458) Pfam (PF00587) Pfam (PF03129) | Homo sapiens (Human) | Glycine--tRNA ligase, GlyRS |
| 2 | B (A) | BIS(ADENOSINE)-5'-TETRAPHOSPHATE | non-polymer | 836.4 | 1 | Chemie (B4P) PubChem (24867496) PubChem (44286171) PubChem (54592217) PubChem (58298222) PubChem (194) PubChem (21706) PubChem (118705482) PubChem (6603812) PubChem (6328499) PubChem (11513435) PubChem (11957522) PubChem (10795591) PubChem (13455592) PubChem (13455593) PubChem (146121073) PubChem (171904579) | |||
| 3 | C (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 1 - 685 (UniProt: P41250)
| PDB | External Database | Details |
|---|---|---|
| Leu 686 | - | expression tag |
| Glu 687 | - | expression tag |
| His 688 | - | expression tag |
| His 689 | - | expression tag |
| His 690 | - | expression tag |
| His 691 | - | expression tag |
| His 692 | - | expression tag |
| His 693 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 78704.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 836.4 | |
| All* | Total formula weight | 79541.2 |
