2ZV2
Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 298 | 33607.7 | 1 | UniProt (Q96RR4) Pfam (PF00069) In PDB | Homo sapiens (Human) | Calcium/calmodulin-dependent protein kinase kinase beta, CaM-kinase kinase beta, CaM-KK beta, CaMKK beta |
| 2 | A | 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid | non-polymer | 314.3 | 1 | Chemie (609) | |||
| 3 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 159 - 449 (UniProt: Q96RR4)
| PDB | External Database | Details |
|---|---|---|
| Gly 152 | - | expression tag |
| Ser 153 | - | expression tag |
| Ser 154 | - | expression tag |
| Gly 155 | - | expression tag |
| Ser 156 | - | expression tag |
| Ser 157 | - | expression tag |
| Gly 158 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33607.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 314.3 | |
| All* | Total formula weight | 33922.0 |
