2ZQ0

Crystal structure of SusB complexed with acarbose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Alpha-glucosidase (Alpha-glucosidase SusB)	polymer	738	84418.6	2	UniProt (P71094) Pfam (PF14508) Pfam (PF10566) Pfam (PF14509) UniProt (by SIFTS) (G8JZS4)	Bacteroides thetaiotaomicron
2	C, D (C, D)	4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		645.6	2	In PDB BIRD (PRD_900007) GlyTouCan (G66431MI)		alpha-acarbose
3	E, F (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	G, H (A, B)	water	water		18.0	1523	Chemie (HOH)

Sequence modifications

A, B: 22 - 738 (UniProt: P71094)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	168837.1
Branched	Number of molecules	2
	Total formula weight	1291.2
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	170208.5

*Water molecules are not included.