2ZMX

Crystal structure of the met1-form of the copper-bound tyrosinase in complex with a caddie protein from Streptomyces castaneoglobisporus obtained by soaking in cupric sulfate solution for 36 hours

Replaces:  1WX3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tyrosinase	polymer	281	32089.6	1	UniProt (Q83WS2) Pfam (PF00264)	Streptomyces castaneoglobisporus
2	B (B)	CADDIE	polymer	134	14203.8	1	Pfam (PF06236) UniProt (by SIFTS) (Q83WS1)	STREPTOMYCES CASTANEOGLOBISPORUS	CADDIE PROTEIN ORF378
3	C, D, E, I (A, B)	COPPER (II) ION	non-polymer		63.5	4	Chemie (CU)
4	F, G, H, J, K (A, B)	NITRATE ION	non-polymer		62.0	5	Chemie (NO3)
5	L, M (A, B)	water	water		18.0	431	Chemie (HOH)

Sequence modifications

A: 1 - 273 (UniProt: Q83WS2)

PDB	External Database	Details
Ser 123	Phe 123	SEE REMARK 999
Leu 274	-	expression tag
Glu 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46293.4
Non-Polymers*	Number of molecules	9
	Total formula weight	564.2
All*	Total formula weight	46857.6

*Water molecules are not included.