2ZJO

Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Genome polyprotein	polymer	482	51875.8	1	UniProt (P29846) Pfam (PF07652) In PDB	Hepatitis C virus (isolate Taiwan) (VIRUSES)
2	A	N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZENAMINIUM	non-polymer		756.8	1	Chemie (BHT)
3		water	water		18.0	67	Chemie (HOH)

Sequence modifications

A: 167 - 631 (UniProt: P29846)

PDB	External Database	Details
Met 156	-	expression tag
Ala 157	-	expression tag
Ser 158	-	expression tag
Met 159	-	expression tag
Thr 160	-	expression tag
Gly 161	-	expression tag
Gly 162	-	expression tag
Gln 163	-	expression tag
Gln 164	-	expression tag
Met 165	-	expression tag
Gly 166	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51875.8
Non-Polymers*	Number of molecules	1
	Total formula weight	756.8
All*	Total formula weight	52632.6

*Water molecules are not included.