2ZJO
Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 482 | 51875.8 | 1 | UniProt (P29846) Pfam (PF07652) Pfam (PF22027) | Hepatitis C virus (isolate Taiwan) (VIRUSES) | |
| 2 | B (A) | N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZENAMINIUM | non-polymer | 756.8 | 1 | Chemie (BHT) | |||
| 3 | C (A) | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence modifications
A: 167 - 631 (UniProt: P29846)
| PDB | External Database | Details |
|---|---|---|
| Met 156 | - | expression tag |
| Ala 157 | - | expression tag |
| Ser 158 | - | expression tag |
| Met 159 | - | expression tag |
| Thr 160 | - | expression tag |
| Gly 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Gln 163 | - | expression tag |
| Gln 164 | - | expression tag |
| Met 165 | - | expression tag |
| Gly 166 | - | expression tag |
| His 632 | - | expression tag |
| His 633 | - | expression tag |
| His 634 | - | expression tag |
| His 635 | - | expression tag |
| His 636 | - | expression tag |
| His 637 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51875.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 756.8 | |
| All* | Total formula weight | 52632.6 |
