2ZIZ
Crystal structure of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with NAD and 3-deazaadenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 495 | 54387.4 | 4 | UniProt (P60176) Pfam (PF05221) Pfam (PF00670) UniProt (by SIFTS) (P9WGV3) | Mycobacterium tuberculosis | S-adenosyl-L-homocysteine hydrolase, AdoHcyase |
| 2 | E, G, J, L (A, B, C, D) | 3-DEAZA-ADENOSINE | non-polymer | 266.3 | 4 | Chemie (AD3) PubChem (1651) PubChem (23190) PubChem (176735355) PubChem (177678932) PubChem (29976739) PubChem (29976742) PubChem (44386188) PubChem (45038778) PubChem (46873944) PubChem (44367024) PubChem (688459) PubChem (46937005) PubChem (59036309) PubChem (92852183) PubChem (93055319) PubChem (94199777) PubChem (12769724) PubChem (12769725) PubChem (124423261) PubChem (134692539) | |||
| 3 | F, H, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 760 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 495 (UniProt: P60176)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 217549.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3718.7 | |
| All* | Total formula weight | 221268.4 |
