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2ZIZ

Crystal structure of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with NAD and 3-deazaadenosine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Adenosylhomocysteinasepolymer49554387.44UniProt (P60176)
Pfam (PF05221)
Pfam (PF00670)
UniProt (by SIFTS) (P9WGV3)
Mycobacterium tuberculosisS-adenosyl-L-homocysteine hydrolase, AdoHcyase
2E, G, J, L
(A, B, C, D)
3-DEAZA-ADENOSINEnon-polymer266.34Chemie (AD3)
3F, H, I, K
(A, B, C, D)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.44Chemie (NAD)
4M, N, O, P
(A, B, C, D)
waterwater18.0760Chemie (HOH)
Sequence modifications
A, B, C, D: 2 - 495 (UniProt: P60176)
PDBExternal DatabaseDetails
Met 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight217549.6
Non-Polymers*Number of molecules8
Total formula weight3718.7
All*Total formula weight221268.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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