2ZI3
C4S-E247A dCK variant of dCK in complex with D-dA+ADP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Deoxycytidine kinase | polymer | 279 | 32514.5 | 2 | UniProt (P27707) Pfam (PF01712) In PDB | Homo sapiens (human) | dCK |
2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
3 | A, B | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol | non-polymer | 251.2 | 2 | Chemie (3D1) | |||
4 | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 260 (UniProt: P27707)
PDB | External Database | Details |
---|---|---|
Met -18 | - | expression tag |
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ser 9 | Cys 9 | engineered mutation |
Ser 45 | Cys 45 | engineered mutation |
Ser 59 | Cys 59 | engineered mutation |
Ser 146 | Cys 146 | engineered mutation |
Ala 247 | Glu 247 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65028.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1356.9 | |
All* | Total formula weight | 66385.8 |