2ZGW

Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with Adenosine and Biotin, Mutations R48A and K111A

Replaces:  2E3Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	biotin--[acetyl-CoA-carboxylase] ligase	polymer	235	25959.3	2	UniProt (O57883) Pfam (PF03099) Pfam (PF02237) In PDB	Pyrococcus horikoshii	Biotin Protein Ligase
2	A, B	ADENOSINE	non-polymer		267.2	2	Chemie (ADN)
3	A, B	BIOTIN	non-polymer		244.3	2	Chemie (BTN)
4		water	water		18.0	584	Chemie (HOH)

Sequence modifications

A, B: 1 - 235 (UniProt: O57883)

PDB	External Database	Details
Ala 48	Arg 48	engineered mutation
Ala 111	Lys 111	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51918.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1023.1
All*	Total formula weight	52941.7

*Water molecules are not included.