2ZCM

Crystal structure of IcaR, a repressor of the TetR family

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Biofilm operon icaABCD HTH-type negative transcriptional regulator icaR	polymer	192	23511.7	2	UniProt (Q5HKQ1) Pfam (PF00440) Pfam (PF18665)	Staphylococcus epidermidis	intercellular adhesion regulator, IcaR repressor, Intercellular adhesion protein R
2	C, D (A, B)	water	water		18.0	857	Chemie (HOH)

Sequence modifications

A, B: 1 - 185 (UniProt: Q5HKQ1)

PDB	External Database	Details
Mse -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Mse 63	Leu 63	engineered mutation
Mse 64	Leu 64	engineered mutation
Mse 143	Leu 143	engineered mutation
Mse 146	Leu 146	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47023.4
All*	Total formula weight	47023.4

*Water molecules are not included.