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2ZAZ

Crystal structure of P38 in complex with 4-anilino quinoline inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMitogen-activated protein kinase 14polymer36041343.21UniProt (Q16539)
Pfam (PF00069)
In PDB
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2AACETATE IONnon-polymer59.01Chemie (ACT)
3A4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehydenon-polymer361.41Chemie (GK1)
4AGLYCEROLnon-polymer92.11Chemie (GOL)
5waterwater18.0363Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41343.2
Non-Polymers*Number of molecules3
Total formula weight512.6
All*Total formula weight41855.8
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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