2ZAK
Orthorhombic crystal structure of precursor E. coli isoaspartyl peptidase/L-asparaginase (EcAIII) with active-site T179A mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | L-asparaginase precursor | polymer | 320 | 33262.7 | 2 | UniProt (P37595) Pfam (PF01112) | Escherichia coli | L-asparagine amidohydrolase |
| 2 | C, F (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 321 (UniProt: P37595)
| PDB | External Database | Details |
|---|---|---|
| Ala 179 | Thr 179 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66525.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 239.0 | |
| All* | Total formula weight | 66764.4 |
