2Z6Q
Ternary structure of Arg165Ala M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3') | polymer | 12 | 3662.4 | 1 | synthetic construct | ||
| 2 | B (D) | DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DG)-3') | polymer | 6 | 1848.3 | 1 | synthetic construct | ||
| 3 | C (E) | DNA (5'-D(*DGP*DCP*DTP*DAP*DTP*DC)-3') | polymer | 6 | 1784.2 | 1 | synthetic construct | ||
| 4 | D (A) | Modification methylase HhaI | polymer | 327 | 36956.1 | 1 | UniProt (P05102) Pfam (PF00145) | Haemophilus parahaemolyticus | HHAI METHYLTRANSFERASE, Cytosine-specific methyltransferase HhaI, M.HhaI |
| 5 | E (A) | 2'-DEOXYCYTIDINE | non-polymer | 227.2 | 1 | Chemie (DCZ) | |||
| 6 | F (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 7 | G, H, I (C, E, A) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A: 1 - 327 (UniProt: P05102)
| PDB | External Database | Details |
|---|---|---|
| Ala 165 | Arg 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44251.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 611.6 | |
| All* | Total formula weight | 44862.6 |
