2Z6A
S-Adenosyl-L-methionine-Dependent Methyl Transfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3') | polymer | 12 | 3662.4 | 1 | synthetic construct | ||
2 | D | DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3') | polymer | 13 | 3966.6 | 1 | synthetic construct | ||
3 | A | Modification methylase HhaI | polymer | 327 | 37010.1 | 1 | UniProt (P05102) Pfam (PF00145) In PDB | Haemophilus parahaemolyticus | HHAI METHYLTRANSFERASE, Cytosine-specific methyltransferase HhaI, M.HhaI |
4 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
5 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 1 - 327 (UniProt: P05102)
PDB | External Database | Details |
---|---|---|
Ala 81 | Cys 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 44639.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 384.4 | |
All* | Total formula weight | 45023.6 |