2Z4B

Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Estrogen receptor beta	polymer	257	29228.6	2	UniProt (Q92731) Pfam (PF00104) In PDB	Homo sapiens (human)	ER-beta
2	A, B	(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL	non-polymer		318.3	2	Chemie (DC8)
3		water	water		18.0	61	Chemie (HOH)

Sequence modifications

A, B: 256 - 505 (UniProt: Q92731)

PDB	External Database	Details
Met 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58457.3
Non-Polymers*	Number of molecules	2
	Total formula weight	636.6
All*	Total formula weight	59093.9

*Water molecules are not included.