2Z3R

Crystal structure of the IL-15/IL-15Ra complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	Interleukin-15	polymer	119	13258.0	8	UniProt (P40933) Pfam (PF02372)	Homo sapiens (human)	IL-15
2	B, D, F, H, J... (B, D, F, H, J...)	Interleukin-15 receptor alpha chain	polymer	107	11496.1	8	UniProt (Q13261)	Homo sapiens (human)	IL-15R-alpha, IL- 15RA
3	Q, R, S, T (A, O)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	AA, BA, CA, DA, EA... (G, H, I, J, K...)	water	water		18.0	519	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K, M, O: 1 - 114 (UniProt: P40933)

PDB	External Database	Details
Ala -4	-	expression tag
Met -3	-	expression tag
Ala -2	-	expression tag
Ile -1	-	expression tag
Ser 0	-	expression tag

B, D, F, H, J, L, N, P: 1 - 102 (UniProt: Q13261)

PDB	External Database	Details
Ala -4	-	expression tag
Met -3	-	expression tag
Ala -2	-	expression tag
Ile -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	198033.2
Non-Polymers*	Number of molecules	4
	Total formula weight	368.4
All*	Total formula weight	198401.6

*Water molecules are not included.