2Z3C
A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Replicase polyprotein 1ab (pp1ab) | polymer | 306 | 33876.6 | 1 | UniProt (P59641) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7) | SARS coronavirus | SARS-CoV 3C-like peptidase |
| 2 | B (B) | inhibitor | polymer | 5 | 601.8 | 1 | BIRD (PRD_000250) | synthetic construct | |
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
B: 307 - 311 (PDB: 2Z3C)
| PDB | External Database | Details |
|---|---|---|
| Kcq 311 | Ecq 5 | microheterogeneity |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34478.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 34570.5 |
