2YY2
Crystal structure of the human Phosphodiesterase 9A catalytic domain complexed with IBMX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | polymer | 333 | 39066.0 | 2 | UniProt (O76083) Pfam (PF00233) In PDB | Homo sapiens (human) | |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 2 | Chemie (IBM) | |||
| 5 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, B: 181 - 506 (UniProt: O76083)
| PDB | External Database | Details |
|---|---|---|
| Gly 174 | - | expression tag |
| Ser 175 | - | expression tag |
| Ser 176 | - | expression tag |
| Gly 177 | - | expression tag |
| Ser 178 | - | expression tag |
| Ser 179 | - | expression tag |
| Gly 180 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78132.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 623.9 | |
| All* | Total formula weight | 78756.0 |
