2YSM

Solution structure of the second and third PHD domain from Histone-lysine N-methyltransferase 2C (KMT2C/MLL3)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog	polymer	111	11879.6	1	UniProt (Q8NEZ4) Pfam (PF00628) In PDB	Homo sapiens (human)	Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3, Homologous to ALR protein
2	A	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

A: 8 - 105 (UniProt: Q8NEZ4)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Ser 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Ser 6	-	expression tag
Gly 7	-	expression tag
Ser 106	-	expression tag
Gly 107	-	expression tag
Pro 108	-	expression tag
Ser 109	-	expression tag
Ser 110	-	expression tag
Gly 111	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	11879.6
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	12141.3

*Water molecules are not included.