2YSM
Solution structure of the second and third PHD domain from Histone-lysine N-methyltransferase 2C (KMT2C/MLL3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog | polymer | 111 | 11879.6 | 1 | UniProt (Q8NEZ4) Pfam (PF00628) | Homo sapiens (human) | Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3, Homologous to ALR protein |
| 2 | B, C, D, E (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A: 8 - 105 (UniProt: Q8NEZ4)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Gly 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Ser 106 | - | expression tag |
| Gly 107 | - | expression tag |
| Pro 108 | - | expression tag |
| Ser 109 | - | expression tag |
| Ser 110 | - | expression tag |
| Gly 111 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11879.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 12141.3 |
