2YQ7
Structure of Bcl-xL bound to BimLOCK
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | BCL-2-LIKE PROTEIN 1 | polymer | 158 | 17918.0 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | HOMO SAPIENS (HUMAN) | BCL-XL, BCL2-L-1, APOPTOSIS REGULATOR BCL-X |
2 | B | BCL-2-LIKE PROTEIN 11 | polymer | 20 | 2213.5 | 1 | UniProt (O43521) Pfam (PF08945) In PDB | HOMO SAPIENS | BIM BETA 5, BCL2-L-11, BCL2-INTERACTING MEDIATOR OF CELL DEATH, BIMEL |
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 1 - 26 (UniProt: Q07817)
B: 147 - 164 (UniProt: O43521)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ace 146 | - | acetylation |
Glu 154 | Arg 154 | engineered mutation |
Lys 158 | Glu 158 | engineered mutation |
Nh2 165 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 20131.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 20223.5 |