2YOF
Plasmodium falciparum thymidylate kinase in complex with a (thio)urea- beta-deoxythymidine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | THYMIDYLATE KINASE | polymer | 210 | 24725.1 | 3 | UniProt (Q8I4S1) Pfam (PF02223) | PLASMODIUM FALCIPARUM | |
| 2 | D, G, J (A, B, C) | 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-3-[[(2R,3S)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methyl]thiourea | non-polymer | 478.9 | 3 | Chemie (74W) | |||
| 3 | E, H, K, L, M (A, B, C) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 4 | F, I (A, B) | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 2 | Chemie (TAM) | |||
| 5 | N, O, P (A, B, C) | water | water | 18.0 | 645 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74175.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2058.3 | |
| All* | Total formula weight | 76233.6 |
