2YM5
Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE CHK1 | polymer | 289 | 33043.0 | 1 | UniProt (O14757) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | CHECKPOINT KINASE 1 |
| 2 | B (A) | (3-{4-[(2S)-2-(AMINOMETHYL)MORPHOLIN-4-YL]-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL}PHENYL)METHANOL | non-polymer | 339.4 | 1 | Chemie (YM5) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33043.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 401.5 | |
| All* | Total formula weight | 33444.4 |
