2YKP
Structure of the human LINE-1 ORF1p trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | LINE-1 ORF1P | polymer | 229 | 27226.3 | 3 | UniProt (Q15605) Pfam (PF17489) Pfam (PF02994) Pfam (PF17490) UniProt (by SIFTS) (Q9UN81) | HOMO SAPIENS (HUMAN) | ORF1 CODES FOR A 40 KDA PRODUCT |
| 2 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) |
Sequence modifications
A, B, C: 104 - 326 (UniProt: Q15605)
| PDB | External Database | Details |
|---|---|---|
| Met 104 | Cys 104 | engineered mutation |
| Ala 105 | Arg 105 | engineered mutation |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| Ala 121 | Met 121 | engineered mutation |
| Ile 125 | Met 125 | engineered mutation |
| Ile 128 | Met 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 81679.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 81749.9 |






