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2YKP

Structure of the human LINE-1 ORF1p trimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
LINE-1 ORF1Ppolymer22927226.33UniProt (Q15605)
Pfam (PF17489)
Pfam (PF02994)
Pfam (PF17490)
UniProt (by SIFTS) (Q9UN81)
HOMO SAPIENS (HUMAN)ORF1 CODES FOR A 40 KDA PRODUCT
2D, E
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
Sequence modifications
A, B, C: 104 - 326 (UniProt: Q15605)
PDBExternal DatabaseDetails
Met 104Cys 104engineered mutation
Ala 105Arg 105engineered mutation
His 327-expression tag
His 328-expression tag
His 329-expression tag
His 330-expression tag
His 331-expression tag
His 332-expression tag
Ala 121Met 121engineered mutation
Ile 125Met 125engineered mutation
Ile 128Met 128engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight81679.0
Non-Polymers*Number of molecules2
Total formula weight70.9
All*Total formula weight81749.9
*Water molecules are not included.

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PDB entries from 2025-10-29

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