2YJF
Oligomeric assembly of actin bound to MRTF-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | ACTIN, ALPHA SKELETAL MUSCLE | polymer | 377 | 42097.0 | 5 | UniProt (P68135) Pfam (PF00022) | ORYCTOLAGUS CUNICULUS (RABBIT) | ALPHA-ACTIN-1 |
| 2 | F (M) | MKL/MYOCARDIN-LIKE PROTEIN 1 | polymer | 137 | 15900.4 | 1 | UniProt (Q8K4J6) Pfam (PF02755) | MUS MUSCULUS (HOUSE MOUSE) | BASIC SAP COILED-COIL TRANSCRIPTION ACTIVATOR, MEGAKARYOBLASTIC LEUKEMIA 1 PROTEIN HOMOLOG, MYOCARDIN-RELATED TRANSCRIPTION FACTOR A, MRTF-A |
| 3 | G, L (A, C) | LATRUNCULIN B | non-polymer | 395.5 | 2 | Chemie (LAB) | |||
| 4 | H, J, M, O, Q (A, B, C, D, E) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 5 | I, K, N, P, R (A, B, C, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) |
Sequence modifications
M: 73 - 199 (UniProt: Q8K4J6)
| PDB | External Database | Details |
|---|---|---|
| Ala 63 | - | expression tag |
| Pro 64 | - | expression tag |
| Gly 65 | - | expression tag |
| Ser 66 | - | expression tag |
| Leu 67 | - | expression tag |
| Ser 68 | - | expression tag |
| Glu 69 | - | expression tag |
| Arg 70 | - | expression tag |
| Lys 71 | - | expression tag |
| Asn 72 | - | expression tag |
| Glu 107 | Arg 50 | conflict |
| Glu 171 | Gly 114 | engineered mutation |
| Arg 172 | Pro 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 226385.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3448.5 | |
| All* | Total formula weight | 229833.6 |
