2YJF
Oligomeric assembly of actin bound to MRTF-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | ACTIN, ALPHA SKELETAL MUSCLE | polymer | 377 | 42097.0 | 5 | UniProt (P68135) Pfam (PF00022) | ORYCTOLAGUS CUNICULUS (RABBIT) | ALPHA-ACTIN-1 |
| 2 | F (M) | MKL/MYOCARDIN-LIKE PROTEIN 1 | polymer | 137 | 15900.4 | 1 | UniProt (Q8K4J6) Pfam (PF02755) | MUS MUSCULUS (HOUSE MOUSE) | BASIC SAP COILED-COIL TRANSCRIPTION ACTIVATOR, MEGAKARYOBLASTIC LEUKEMIA 1 PROTEIN HOMOLOG, MYOCARDIN-RELATED TRANSCRIPTION FACTOR A, MRTF-A |
| 3 | G, L (A, C) | LATRUNCULIN B | non-polymer | 395.5 | 2 | Chemie (LAB) PubChem (16760044) PubChem (20054954) PubChem (3892) PubChem (22832299) PubChem (72940) PubChem (23424960) PubChem (23863831) PubChem (25215545) PubChem (57370013) PubChem (59169653) PubChem (59431496) PubChem (56928133) PubChem (67441199) PubChem (67441200) PubChem (5352046) PubChem (5353712) PubChem (6436219) PubChem (88895461) PubChem (90912141) PubChem (10000783) PubChem (92209860) PubChem (14504487) PubChem (98044136) PubChem (98044137) PubChem (98044135) PubChem (129388766) PubChem (129388767) PubChem (162928966) PubChem (146159701) PubChem (154825202) PubChem (162928961) PubChem (162928962) PubChem (162928963) PubChem (162928964) PubChem (162928965) PubChem (162928967) PubChem (163195209) PubChem (168317464) PubChem (171039486) | |||
| 4 | H, J, M, O, Q (A, B, C, D, E) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 5 | I, K, N, P, R (A, B, C, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) PubChem (888) |
Sequence modifications
M: 73 - 199 (UniProt: Q8K4J6)
| PDB | External Database | Details |
|---|---|---|
| Ala 63 | - | expression tag |
| Pro 64 | - | expression tag |
| Gly 65 | - | expression tag |
| Ser 66 | - | expression tag |
| Leu 67 | - | expression tag |
| Ser 68 | - | expression tag |
| Glu 69 | - | expression tag |
| Arg 70 | - | expression tag |
| Lys 71 | - | expression tag |
| Asn 72 | - | expression tag |
| Glu 107 | Arg 50 | conflict |
| Glu 171 | Gly 114 | engineered mutation |
| Arg 172 | Pro 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 226385.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3448.5 | |
| All* | Total formula weight | 229833.6 |
