2YI1
Crystal structure of N-Acetylmannosamine kinase in complex with N- acetyl mannosamine 6-phosphate and ADP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE | polymer | 343 | 36639.0 | 1 | UniProt (Q9Y223) Pfam (PF00480) | HOMO SAPIENS (HUMAN) | N-ACETYL MANNOSAMINE KINASE, MANAC KINASE, UDP-GLCNAC-2-EPIMERASE/MANAC KINASE |
| 2 | B (A) | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose | non-polymer | 301.2 | 1 | Chemie (BMX) | |||
| 3 | C (A) | 2-acetamido-2-deoxy-alpha-D-mannopyranose | non-polymer | 221.2 | 1 | Chemie (BM3) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | G (A) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
| 7 | H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | I, J, K, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 9 | M (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 10 | N (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 11 | O (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 12 | P (A) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 406 - 720 (UniProt: Q9Y223)
| PDB | External Database | Details |
|---|---|---|
| Met 378 | - | expression tag |
| Gly 379 | - | expression tag |
| Ser 380 | - | expression tag |
| Ser 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| Ser 388 | - | expression tag |
| Ser 389 | - | expression tag |
| Gly 390 | - | expression tag |
| Leu 391 | - | expression tag |
| Val 392 | - | expression tag |
| Pro 393 | - | expression tag |
| Arg 394 | - | expression tag |
| Gly 395 | - | expression tag |
| Ser 396 | - | expression tag |
| His 397 | - | expression tag |
| Met 398 | - | expression tag |
| Glu 399 | - | expression tag |
| Asn 400 | - | expression tag |
| Leu 401 | - | expression tag |
| Tyr 402 | - | expression tag |
| Phe 403 | - | expression tag |
| Gln 404 | - | expression tag |
| Gly 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36639.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2035.5 | |
| All* | Total formula weight | 38674.5 |
