2YI1
Crystal structure of N-Acetylmannosamine kinase in complex with N- acetyl mannosamine 6-phosphate and ADP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE | polymer | 343 | 36639.0 | 1 | UniProt (Q9Y223) Pfam (PF00480) | HOMO SAPIENS (HUMAN) | N-ACETYL MANNOSAMINE KINASE, MANAC KINASE, UDP-GLCNAC-2-EPIMERASE/MANAC KINASE |
| 2 | B (A) | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose | non-polymer | 301.2 | 1 | Chemie (BMX) PubChem (46936841) PubChem (101265229) PubChem (124524505) PubChem (124761964) PubChem (124761965) PubChem (135071263) PubChem (145708105) PubChem (163060211) PubChem (172138841) PubChem (172138855) PubChem (172641766) PubChem (898) PubChem (440273) PubChem (11426583) PubChem (11522296) PubChem (439219) PubChem (440996) PubChem (10040501) PubChem (16019956) | |||
| 3 | C (A) | 2-acetamido-2-deoxy-alpha-D-mannopyranose | non-polymer | 221.2 | 1 | Chemie (BM3) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E, F (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 6 | G (A) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) PubChem (4867) | |||
| 7 | H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 8 | I, J, K, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 9 | M (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 10 | N (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 11 | O (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 12 | P (A) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 406 - 720 (UniProt: Q9Y223)
| PDB | External Database | Details |
|---|---|---|
| Met 378 | - | expression tag |
| Gly 379 | - | expression tag |
| Ser 380 | - | expression tag |
| Ser 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| Ser 388 | - | expression tag |
| Ser 389 | - | expression tag |
| Gly 390 | - | expression tag |
| Leu 391 | - | expression tag |
| Val 392 | - | expression tag |
| Pro 393 | - | expression tag |
| Arg 394 | - | expression tag |
| Gly 395 | - | expression tag |
| Ser 396 | - | expression tag |
| His 397 | - | expression tag |
| Met 398 | - | expression tag |
| Glu 399 | - | expression tag |
| Asn 400 | - | expression tag |
| Leu 401 | - | expression tag |
| Tyr 402 | - | expression tag |
| Phe 403 | - | expression tag |
| Gln 404 | - | expression tag |
| Gly 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36639.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2035.5 | |
| All* | Total formula weight | 38674.5 |
