2YGF
L89V, L93I and V136M Mutant of N-Term HSP90 complexed with Geldanamycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 | polymer | 220 | 24891.4 | 1 | UniProt (P02829) Pfam (PF02518) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | 82 KDA HEAT SHOCK PROTEIN, HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM, HSP90 |
| 2 | A | GELDANAMYCIN | non-polymer | 560.6 | 1 | Chemie (GDM) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A: 1 - 220 (UniProt: P02829)
| PDB | External Database | Details |
|---|---|---|
| Val 89 | Leu 89 | engineered mutation |
| Ile 93 | Leu 93 | engineered mutation |
| Met 136 | Val 136 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24891.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 652.7 | |
| All* | Total formula weight | 25544.2 |
