2YEX
Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | SERINE/THREONINE-PROTEIN KINASE CHK1 | polymer | 276 | 31840.7 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CHK1 CHECKPOINT KINASE |
2 | A | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
3 | A | 5-METHYL-8-(1H-PYRROL-2-YL)[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1(2H)-ONE | non-polymer | 264.3 | 1 | Chemie (YEX) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
5 | water | water | 18.0 | 448 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31840.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1005.0 | |
All* | Total formula weight | 32845.7 |